https://github.com/pypa/setuptools/security/advisories/GHSA-5rjg-fvgr-3xxf reports:
setuptools is a package that allows users to download, build,
install, upgrade, and uninstall Python packages. A path traversal
vulnerability in `PackageIndex` is present in setuptools prior to
version 78.1.1. An attacker would be allowed to write files to
arbitrary locations on the filesystem with the permissions of the
process running the Python code, which could escalate to remote
code execution depending on the context.